Television talk-show host, actress, and producer. Born January 29, 1954, in Kosciusko, Mississippi. After a troubled adolescence in a small farming community, where she was sexually abused by a number of male relatives and friends of her mother, Vernita, she moved to Nashville to live with her father, Vernon, a barber and businessman. She entered Tennessee State University in 1971 and began working in radio and television broadcasting in Nashville.

In 1976, Winfrey moved to Baltimore, where she hosted the TV chat show, People Are Talking. The show became a hit and Winfrey stayed with it for eight years, after which she was recruited by a Chicago TV station to host her own morning show, A.M. Chicago. Her major competitor in the time slot was Phil Donahue. Within several months, Winfrey’s open, warm-hearted personal style had won her 100,000 more viewers than Donahue and had taken her show from last place to first in the ratings. Her success led to nationwide fame and a role in Steven Spielberg’s 1985 film, The Color Purple, for which she was nominated for an Academy Award for Best Supporting Actress.

Winfrey launched the Oprah Winfrey Show in 1986 as a nationally syndicated program. With its placement on 120 channels and an audience of 10 million people, the show grossed $125 million by the end of its first year, of which Winfrey received $30 million. She soon gained ownership of the program from ABC, drawing it under the control of her new production company, Harpo Productions (“Oprah” spelled backwards) and making more and more money from syndication.

In 1994, with talk shows becoming increasingly trashy and exploitative, Winfrey pledged to keep her show free of tabloid topics. Although ratings initially fell, she earned the respect of her viewers and was soon rewarded with an upsurge in popularity. Her projects with Harpo have included the highly rated 1989 TV miniseries, The Women of Brewster Place, which she also starred in. Winfrey also signed a multi-picture contract with Disney. The initial project, 1998’s Beloved, based on Pulitzer Prize-winning novel by Toni Morrison and starring Winfrey and Danny Glover, got mixed reviews and generally failed to live up to expectations.

Winfrey, who became almost as well-known for her weight loss efforts as for her talk show, lost an estimated 90 pounds (dropping to her ideal weight of around 150 pounds) and competed in the Marine Corps Marathon in Washington, DC, in 1995. In the wake of her highly publicized success, Winfrey’s personal chef, Rosie Daley, and trainer, Bob Greene, both published best-selling books.

The media giant contributed immensely to the publishing world by launching her “Oprah’s Book Club,” as part of her talk show. The program propelled many unknown authors to the top of the bestseller lists and gave pleasure reading a new kind of popular prominence. With the debut in 1999 of Oxygen Media, a company she co-founded that is dedicated to producing cable and Internet programming for women, Winfrey ensured her place in the forefront of the media industry and as one of the most powerful and wealthy people in show business. Her magazine, O: The Oprah Magazine debuted in April 2000.

Winfrey is a dedicated activist for children’s rights; in 1994, President Clinton signed a bill into law that Winfrey had proposed to Congress, creating a nationwide database of convicted child abusers. She founded the Family for Better Lives foundation and also contributes to her alma mater, Tennessee State University. Since 1992, Winfrey has been engaged to Stedman Graham, a public relations executive. The couple lives in Chicago, and Winfrey also has homes in Rolling Prairie, Indiana, and Telluride, Colorado.

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